SHARP-2

Scalable Digital Phenotyping of Momentary Cognition in Early Course Psychosis

Overview

This project aims to address challenges around the assessment of cognition as well as its measurement in the context of different environments and circadian terms through a novel concept called micro cognitive and contextual momentary performance.

Micro cognitive and contextual momentary performance metrics involve two core elements captured simultaneously:

1) brief self-administered scalable smartphone measures of cognitive performance; and

2) digital phenotyping measures of symptoms, activity levels, sleep patterns, and related functional/environmental factors.

The SHARP project is centred around the objective of scalable digital phenotyping of momentary cognition in early-course psychosis. In this initiative, we are collaborating with schizophrenia patients diagnosed at AIIMS Bhopal. The project spans across three sites: AIIMS Bhopal, Nimhans, and BIDMC Boston.

Rationale

Clinically, administering cognitive assessments such as the MATRICS™ Consensus Cognitive Battery (MCCB™) or BACS takes more time than is available in the standard patient visit. There are also fewer assessments for remote administration, which creates additional hurdles. This study attempt to address these challenges around the assessment of cognition as well as its measurement in the context of different environments and circadian terms through a novel concept called micro cognitive and contextual momentary performance. Micro cognitive and contextual momentary performance metrics involve two core elements captured simultaneously: 1) brief self-administered scalable smartphone measures of cognitive performance; and 2) digital phenotyping measures of symptoms, activity levels, sleep patterns, and related functional/environmental factors.