PREMIUM

PREMIUM

Project name Program for Effective Mental health Interventions in Under-resourced health systems (PREMIUM)
Objective
  • To define the steps of a systematic methodology for the development of new psychological treatment for delivery by community or lay health workers (CLHW)
  • To test this methodology in the development of treatment for Depressive Disorder (DD) and Alcohol Use Disorders (AUD)
  • To evaluate the clinical benefit and cost effectiveness of the resulting treatments
  • To develop a framework for scaling up psychological treatment delivered by CLHW
Dates October 2010 to August 2016
Principal investigator Prof Vikram Patel
Sites 10 Primary Health Centres (PHCs) in Goa
Study design 2 Randomised Controlled Trials of the effectiveness and cost-effectiveness of lay counsellor-delivered psychological treatments for harmful drinking (CAP) and moderate to severe depression (HAP) in primary care in India Vs. Enhanced Usual Care.
Sample description Health Activity Program (HAP) N= 493 adults patients screened positive for moderate to severe depression on PHQ9 recruited and followed-up at 3 and 12 monthsCounseling for Alcohol Problems (CAP) N=377 male adults patients screened positive on AUDIT for harmful drinking recruited and followed-up at 3 and 12 months
Sample size HAP = 493 PatientsCAP = 377 Patients
Randomisation Randomised Controlled Trials (Individual Allocation)
Recruitment: No of participants HAP = 493 Patients enrolled from 10 Primary Health Centres (PHCs)CAP = 377 Patients enrolled from 10 Primary Health Centres (PHCs) in Goa
Intervention models Enhanced Usual Care Model versus Health Activity Program (HAP) ModelEnhanced Usual Care Model versus Counseling for Alcohol Problems (CAP)
Codebook available Yes
Instruments used Socio-economic data,TLFB,

AUDIT,

PHQ9,

BDI-II

Suicidal behavior

Violence

WHODAS,

Cost Service Receipt Inventory

Database type SPSS23, STATA 13
Database description HAP Trial: Individual level data on severity of symptoms of depression, suicidal behaviour and levels of disability and costs related to illnessCAP Trial: Individual level data on Quantity/ frequency Alcohol Use and severity of symptoms of Alcohol use Disorders, suicidal behaviour and levels of disability and costs related to illness.
Funder The Wellcome Trust, UK, through the London School of Hygiene & Tropical Medicine
Collaborating institutions London School of Hygiene & Tropical Medicine, UK; Wellcome Trust; Directorate of Health Services of Goa & Sangath